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The fungal α-aminoadipate pathway for lysine biosynthesis requires two enzymes of the aconitase family for the isomerization of homocitrate to homoisocitrate

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Keywords: oxidative stress, NADPH oxidases, ROS, mitochondrial dysfunction, redox-sensitive signaling pathways, inflammation, fibrosis, vascular remodeling, hypertension, renal dysfunction, chronic kidney disease, Nrf2/ARE pathway, NF-κB signaling, renin–angiotensin–aldosterone system (RAAS), angiotensin II, TGF-β signaling, antioxidants, SGLT2 inhibitors, MR receptor antagonists 1