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Tumors secrete angiogenic growth factors that can downregulate endothelial adhesion molecules essential for the interactions with granulocytes, macrophages, and natural killer cells on the vascular endothelium (Griffioen, 2008)

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It was discovered that PD patients had higher levels of oligomeric α-Syn and a higher ratio of oligomeric α-Syn to t-α-Syn in the saliva than those of controls (Cao et al., 2019)