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This molecule acts as a biological "cleanup crew." It neutralizes free radicals—unstable atoms that can damage cells, proteins, and DNA

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Its structure includes the Broad Complex Tram track and Bric-a-Brac (BTB) domain for dimerization and Cul3 interaction, the intervening region (IVR) containing redox-sensitive cysteine residues (e.g., Cys151) and the Kelch domain, which binds the ETGE and DLG motifs of Nrf2 [19]