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Furthermore, it has been demonstrated that increases in MGP inactive form are linked to early vascular disease symptoms as well as cardiovascular morbidity and mortality (139–143)

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A shift in carbon flux from β-oxidation to the riboflavin biosynthetic pathway was proved by a twofold increase in ADE1 , RIB1 , and RIB5 protein synthesis, and in gene expression of gluconeogenesis and pentose phosphate cycles, but it was observed that the downregulation of pathways were related to carbon source assimilation, energy generation, and glycolysis at the riboflavin-producing phase (Table 3

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